9:00 Registrations of participants

09:15: Welcome from the Humanitas University and Humanitas Cancer Center

09:30: Opening of the congress
             P. Nicolai (Padova, Italy) – G. Spriano (Milan, Italy)

09:50 Introduction: Presentation of the project
             P. Bossi (Milan, Italy), M. Ferrari (Padova, Italy)

10:20 – 11:00 Session 1 – Moderator: A Paderno
I. Granular indications for T2-T3 cancer, Indications for T4a laryngeal cancers
    I. Vilaseca (Barcelona, Spain), G. Peretti (Genova, Italy)
II. Approved and rejected statements
     F. Mularoni (Padova, Italy)

11:00- 11:30 Session 2 – Moderator: M Ferrari
I. Indications for salvage organ preservation strategies after RT failure
    G. Succo (Torino, Italy)
II. How to prevent complications after salvage surgery
G. Mercante (Milan, Italy)

II. Approved and rejected statements
     P. Gaudioso (Padova, Italy)

11:30- 12:00 Session 3 – Moderator: MG Ghi
I. Prognostic/predictive factors in laryngeal/hypopharyngeal cancers
   A. Psyrri (Athens, Greece)
II. Approved and rejected statements
    D. Smussi (Brescia, Italy)

12:00 -12:40 Session 4– Moderator: C. Giannitto
I. Cost-effectiveness of different laryngeal preservation approaches
    C. Rognoni (Milano, Italy)
II. Follow-up
    R. Maroldi (Brescia, Italy)
III. Approved and rejected statements
      C. Pessina (Padova, Italy)

12:40- 13:30 Light lunch

13:30-14:30 The Preserve project: example of a tailored approach to laryngeal and hypopharyngeal cancers.  Presentation of the preliminary results of the project funded by the Era PerMed JTC2020 grant
P. Bossi (Milan, Italy), S. Calza (Brescia, Italy), M. Plana (Barcellona, Spain),
S. Chiocca (Milan, Italy), D. Mattavelli (Brescia, Italy)

14:30 – 15:30 Session 5   Moderator: C. Franzese
I. Laryngeal function at baseline: assessment (minimal criteria for definition) and value for preservation strategies
    K. Harrington (London, UK)
II. Which comorbidities are contraindications and at what extent? (neurological, cardiovascular, pulmonary)
     N. Battisti (London, UK)
III. Prehabilitation and rehabilitation protocols.
      R. Martino (Toronto, Canada), A. Schindler (Milan, Italy)
IV. Approved and rejected statements
      C. Resteghini (Milan, Italy)

15:30- 16:00 Session 6 – Moderator: M Krengli
I. Organ preservation in older patients: selection criteria
   P. Szturz (Lausanne, Switzerland)
II. Approved and rejected statements
     C. Gurizzan (Milan, Italy)

16:00 – 16:30 Coffee break

16:30- 17:00 Session 7 – Moderator:  M. Scorsetti
I. Listen to patient’s preferences: tools and implementation
    V. Gregoire (Lyon, France)
II. Approved and rejected statements
     V. Gregoire (Lyon, France)

17:00 – 18:00 Session 8
I. What changes now? What are the topics still to be clarified? Which are the not approved statements and why? Which new study is needed? Which role for immunotherapy in the treatment of recurrent/metastatic laryngeal/hypopharyngeal cancer?
    P. Bossi (Milan, Italy), M. Ferrari (Padova, Italy), P. Nicolai (Padova, Italy)

18:30 End of works – Thanks and greetings